Welcome to the Research Histology Core!
Histological assessment is widely used to evaluate changes in tissue structure, cellular composition and biomarker expression in basic, translational and clinical research. The Research Histology Core (RHC) provides high-quality, reliable histology services to support the research community at UIC and external investigators.
Our facility offers a full range of routine histological services, including tissue processing, embedding, and sectioning of FFPE and frozen samples. We provide a variety of standard and advanced staining techniques, including H&E, special stains, chromogenic immunohistochemistry, multiplex immunofluorescence (IF) and in situ hybridization (ISH/RNAscope). Our team works with many sample types, including preclinical animal models (mouse, rat, rabbit, pig and zebrafish), 3D cell culture models, and human tissues. All services are core-assisted, and we also offer training on cryostat and microtome use.
The RHC collaborates closely with the UIC Biorepository (BIOR), the Spatial and Genome Technologies Core, and the Research Tissue Imaging Core to deliver a comprehensive experimental workflow from tissue procurement to image analysis. We support researchers at every step of their project, from experimental planning to slide interpretation. To request services or schedule instrument time, please visit our iLab.
Header image is a triple-positive invasive ductal breast cancer stained with Opal TSA dyes for HER2, ER, panCK and DAPI; scanned at 20x on a Vectra 3 system.
Core Director
Faculty Advisor
Faculty Advisory Committee
Ron Gaba, MD, MS
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Lisa Tussing-Humphreys, PhD
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Abeer Mohamed, MD, PhD
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Ekrem Emrah Er, PhD
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Alexandra Naba, PhD
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Peter H. Gann, MD, ScD
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Research Resources Center Cores
Research Resources Center
Meet the Research Resources Center
The Research Resources Center (RRC) is a division of the Office of the Vice Chancellor for Research at the University of Illinois Chicago. The RRC offers research faculty, staff, and students a diverse inventory of high-end scientific equipment as well as a wide range of services offered by 18 core facilities staffed with highly skilled scientists. In addition, our staff trains the research faculty, staff and students to use the scientific equipment. Through the RRC, researchers also have access to statistical and computational support for data handling, data transfer, and interpretation of experimental results. The RRC Scientific Store supports research on campus by supplying over 1300 items while Scientific Instrument Shop can fabricate one-of-a-kind models and repair complex scientific equipment. The RRC also welcomes external users doing scientific research.